E2DR: Energy Efficient Data Replication in Data Grid

Abstract— Data grids are an important branch of gird computing which provide mechanisms for the management of large volumes of distributed data. Energy efficiency has recently emerged as a hot topic in large distributed systems. The development of computing systems is traditionally focused on performance improvements driven by the demand of client's applications in scientific and business domains. High energy consumption in computer systems leads to their limited performance because of the increased consumption of carbon dioxide and amount of electricity bills. Thus, the goal of design of computer systems has been shifted to power and energy efficiency. Data grids can solve large scale applications that require a large amount of data. Data replication is a common solution to improve availability and file access time in such environments. This solution replicates the data file in many different sites. In this paper, a new data replication method is proposed that is not only data aware, but also is energy efficient. Simulation results with CLOUDSIM show that the proposed method gives better energy consumption, average response time, and network usage than other algorithms and prevents the unnecessary creation of replica, which leads to efficient storage usage

The Position of Exegetic Hadiths Narrated by Holy Prophet's Household (p.b.u.t) in Zad Al-Masir Exegesis

(Received: 9/2/1396-29/4/2017; Accepted: 8/5/1396-30/7/2017)   Abstract Both Sunni and Shia commentators have referred to the hadiths narrated by Holy Prophet's household (p.b.u.t) from the beginning of compiling exegetic sources. Sunni commentators have differently approached to these hadiths. Some of them have cited and criticized them extensively and fairly, while others have rarely referred to them and criticized them unfairly. The present paper seeks to show how Ibn Jawzi, the famous Sunni commentator in the sixth century ('AH'), have attended and approached to these hadiths. The results show that these hadiths have not a proper and considerable position in his exegesis, because he had not only referred to them in very few cases, but also has criticized them unfairly. Many hadiths attributed to Imam Ali and other Imams in his exegesis are regarded weak hadiths

Employee Mental Absence Diagnosing and Analysis of Digital Mental Health Platforms (Case study: Iran Tobacco Company)

Purpose: The purpose of this study is to investigate the diagnosis of employees' mental absence and to provide a suitable model for the Iranian Tobacco Company. Method: This research was conducted with a qualitative-inductive approach and the method of Strauss-Corbin's grounded theory. The research tool (data collection) is a semi-structured interview that analyzes the data obtained from interviews with 10 qualified elites and experts of the Iranian Tobacco Company in three stages of open, axial, and selective coding in ATLAS TI software using the grounded theory method. Findings: 13 general categories in the form of a paradigm model in which these factors include causal conditions (individual factors; factors of group behavior; organizational factors; environmental factors), axial phenomenon (diagnosis of the mental absence of employees), contextual conditions (environmental and physical context), intervening conditions (individual factors ), and strategies (organizational strategy; job-related strategy; career development strategy), and consequences (individual outcomes; effectiveness; group outcomes) were identified. Conclusion: In a business environment with digital disruption from competitors and customers who have more choices through the availability of digital applications and information, it is important to ensure that organizations can quickly understand and adapt to new information. The need for mindfulness and control of mental absence is a prerequisite for digital transformation

Effects of Cream Containing Rhamnolipid Microbial Surfactants from Pseudomonas aeruginosa MR01 on Growth Inhibition of Staphylococcus aureus

Background and purpose: Dramatic increase in antibiotic-resistant bacteria highlights the need for new compounds with more effective antibacterial properties and biotechnology could be useful in producing these metabolites. The present study aimed at investigating the effects of rhamnolipid microbial surfactants in a cream-based formulation on growth inhibition of Staphylococcus aureus using in vitro and animal models. Materials and methods: The inhibitory effects of rhamnolipids produced by Pseudomonas aeruginosa MR01 on the growth of S. aureus were investigated by disk diffusion method. Then, the effects of dirhamnolipid compounds on the survival and morphology of bacteria were studied using estimation of colony forming units (CFUs) and scanning electron microscopy (SEM). The di-rhamnolipid-containing cream was prepared and its effects on inhibition of the bacterial growth was evaluated in in vitro and animal subjects. Results: Disk diffusion tests showed a minimum inhibitory value of 30mg/disk for aqueous solutions of mono- and di-rhamnolipids, and 20mg/disk and 10mg/disk for mono- and di-rhamnolipid solutions in Dimethyl sulfoxide (DMSO), respectively. The aqueous solution of di-rhamnolipids at 20mg/ml resulted in lack of viable cells of S. aureus. SEM images showed changes in spherical shape of S. aureus during rhamnolipid treatments. Di-rhamnolipid-containing cream led to inhibition of bacterial growth in vitro on agar medium. Moreover, findings in rats indicated inhibition of bacterial growth in wound areas after 20 days of treatment with the cream. Conclusion: In current study, Di-rhamnolipids demonstrated inhibitory effects on the growth of S. aureus. These compounds in cream formulation could also have antibacterial effects

Employee Mental Absence Diagnosing and Analysis of Digital Mental Health Platforms (Case study: Iran Tobacco Company)

Purpose: The purpose of this study is to investigate the diagnosis of employees' mental absence and to provide a suitable model for the Iranian Tobacco Company.Method: This research was conducted with a qualitative-inductive approach and the method of Strauss-Corbin's grounded theory. The research tool (data collection) is a semi-structured interview that analyzes the data obtained from interviews with 10 qualified elites and experts of the Iranian Tobacco Company in three stages of open, axial, and selective coding in ATLAS TI software using the grounded theory method.Findings: 13 general categories in the form of a paradigm model in which these factors include causal conditions (individual factors; factors of group behavior; organizational factors; environmental factors), axial phenomenon (diagnosis of the mental absence of employees), contextual conditions (environmental and physical context), intervening conditions (individual factors ), and strategies (organizational strategy; job-related strategy; career development strategy), and consequences (individual outcomes; effectiveness; group outcomes) were identified.Conclusion: In a business environment with digital disruption from competitors and customers who have more choices through the availability of digital applications and information, it is important to ensure that organizations can quickly understand and adapt to new information. The need for mindfulness and control of mental absence is a prerequisite for digital transformation

Autoantibodies against Central Nervous System Antigens and the Serum Levels of IL-32 in Patients with Schizophrenia

Background: Schizophrenia is a disease of the nervous system, and immune system disorders can affect its pathogenesis. Activation of microglia, proinflammatory cytokines, disruption of the blood-brain barrier due to inflammation, activation of autoreactive B cells, and consequently the production of autoantibodies against system antigens are among the immune processes involved in neurological diseases. Interleukin-32 (IL-32) is a proinflammatory cytokine that is essential in activating innate and adaptive immune responses. This study aimed to measure the serum level of IL-32 as well as the frequency of autoantibody positivity against several nervous system antigens in patients with schizophrenia. Material and Methods: This study was conducted on 40 patients with schizophrenia and 40 healthy individuals in the control group. Serum IL-32 levels were measured by ELISA. The frequency of autoantibodies against Hu, Ri, Yo, Tr, CV2, amphiphysin, SOX1, Zic4, ITPR1, CARP, glutamic acid decarboxylase GAD, recoverin, titin, and ganglioside antigens was measured by the indirect immunofluorescence method. Results: Serum IL-32 levels in patients with schizophrenia were significantly higher compared to the control group. The frequency of autoantibodies against GAD and RI antigens in patients with schizophrenia was significantly higher than in the control group. Autoantibodies were positive in 8 patients for GAD antigen and 5 patients for RI antigen. Autoantibodies were also positive in 2 patients for CV2, 1 patient for Hu, and 1 patient for CARP. Negative results were reported for other antigens. Conclusion: Our findings suggest that elevated the serum IL-32 level and autoantibodies against GAD and RI antigens may be a reflection of immune system dysregulation in patients with schizophreni

Allopurinol prophylactic therapy and the prevention of contrast-induced nephropathy in high-risk patients undergoing coronary angiography: A prospective randomized controlled trial

BACKGROUND: Contrast-induced nephropathy (CIN) is considered to be a possibly severe complication of radiography and thus, remains to be the main cause of acute kidney injury (AKI) for inpatients. A clinical trial was executed to measure the preventive effect of allopurinol against CIN in high-risk patients undertaking coronary angiography. METHODS: Through randomized controlled trial, 140 patients with at minimum two risk factors of CIN, undertaking coronary angiography, were randomly allocated to the allopurinol (n = 70) or control group (n = 70). Those in the allopurinol group received allopurinol (300 mg) a day before their coronary angiography and intravenous hydration for 12 hours before and after their procedure, while members of the control group only received intravenous hydration. Serum creatinine (SCr), blood urea nitrogen (BUN) and uric acid were measured before and 48 hours after the procedure. CIN was defined by a 25% increase in SCr or the concentration of &gt; 0.5 mg/dl, 48 hours after coronary angiography. RESULTS: CIN was observed in 8 (11.4%) patients in the allopurinol group and 11 (15.7%) patients in the control group. There was no significant difference in the incidence of CIN between the two groups at 48 hours after coronary angiography (P = 0.459). In the allopurinol group, the median SCr concentration decreased non-significantly from 1.16 mg/dl to 1.13 mg/dl, 48 hours after coronary angiography (P = 0.189). In the control group, the median SCr concentration increased significantly from 1.11 mg/dl to 1.2 mg/dl, 48 hours after coronary angiography (P &lt; 0.001). CONCLUSION: Allopurinol presents no considerable effectiveness over the hydration protocol for development of CIN in high-risk patients.&nbsp;</p

A Study of Autoantibodies Against some Central Nervous System Antigens and the IL-35 Serum Level in Schizophrenia

Schizophrenia (SCZ) is a debilitating mental disorder with various causes involving complex interactions between genetic factors and environmental agents. The immune system plays a vital role in the pathology and function of the nervous system. Interleukin 35 (IL-35) is a regulatory and anti-inflammatory cytokine that can prevent autoimmune and inflammatory diseases. This study aimed to investigate the role of autoantibodies against some central nervous system (CNS) antigens and IL-35 serum levels in patients with Schizophrenia. This case-control study involved 80 participants. The serum levels of IL-35 were measured by enzyme-linked immunosorbent assay and the autoantibodies in the CNS by indirect immunofluorescence assay (TEA). The serum levels of IL-35 were decreased in patient groups compared to healthy subjects. Autoantibodies against N-methyl-D-aspartate receptor (NMDAR) and myelin-associated glycoprotein (MAG) were positive in 15% (6/40) and 7.5% (3/40), respectively; however, no antibodies against myelin, aquaporin-4 (AQP4), myelin oligodendrocyte glycoprotein (MOG), voltage-gated potassium channel (VGKC), alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPAR), gamma-butyric acid receptor type B1 gamma-butyric acid receptor type B1 (GABABR), antidipeptidyl peptidase-like protein-6 (DPPX), immunoglobulm-like cell adhesion molecule 5 (IgLON5), Glycine receptor (R) and acetylcholine receptor (Ach R) were detected (No statistics were computed). We found that decreased serum IL-35 levels and the existence autoantibodies against NMDAR antigen may contribute to the pathogenesis of SCZ

Iodine Concentration in Iodized Salts Marketed in Lorestan Province, West of Iran

Iodine as a trace micronutrient has important role in body physiology and its sufficient intake is essential for synthesize and secrete adequate amounts of thyroid gland hormones which influenced all periods of human life including fetal, childhood and adolescence. The aim of this study was to evaluate iodine concentration in marketed edible salt samples in Lorestan Province, comparing with existing standards and offering solutions necessary to fix the probably problems. Two hundred and forty samples of 20 brands of marketed edible salt were purchased randomly of eight cities in Lorestan Province during April 2014 to March 2015. Iodine concentration was measured by titration method. Results showed that iodine concentration in 64.59% of salt samples was in acceptable limits according national standard of Iran during this study. A significant number of nonstandard samples showed violation of salt factories of regulations and their noncompliance to mandatory standards. Due to importance of iodine in human health and valuable role in the vital functions of the body at different periods of human life and to avoid violations of iodized salts manufacturers, regular control of marketed salts and enforcement of laws and regulations are recommended.aflatoxin production in treated nuts